Neuropathy testing can help diagnose small fiber neuropathy by testing a small sample of your epidermal nerve’s fiber density, often referred to as ENFD. Neuropathy is a peripheral nerve disease that selectively affects small diameter nerve fibers. Skin biopsy measuring epidermal nerve fiber density is a well-established method used to help evaluate small fiber neuropathy. Common causes of small fiber neuropathy are diabetes (types 1 and 2), HIV, vibratory trauma, amyloidosis/monoclonal gammopathy, alcohol abuse, pharmacologic toxins, solvent exposure, and/or idiopathic neuropathy. Your Eugene Podiatry foot specialists specialize in neuropathy testing and will work with you step by step on a diagnosis and treatment plan.